Posted to MedZilla on 2/19/2019

Takeda Pharmaceuticals

US-CA, Laboratory Scientist SR0031145-MZ


Executing process development projects, process improvement and scale down projects, technology transfer, and support of manufacturing operations.

Essential Duties and Responsibilities

  • Performs experiments in small scale that leads to assess process or final product impact with regard to process deviations or process changes/improvements for the global plasma network.
  • Evaluates performance and suitability of new technologies and process changes by testing and reporting different critical parameters set out in evaluation protocols or run-sheets/templates.
  • Performs trials and experiments, participate into the design and scale-up of new technologies.
  • Actively participates in development, qualification, and maintenance of the scale-down models.
  • Conducts routine bases analytical tests to evaluate and control product yield, purity and impurity profiles of products that are manufactured in the Vienna/Los Angeles/Covington/Lessines facility.
  • Works closely with other Lab Scientists to support the upkeep, maintenance, and efficient utilization of the lab.
  • Supervise temporary employees when required. Write SOPs and batch records, and develop research outlines for scientific projects.
  • Utilize robust statistical analysis to draw appropriate conclusions from the data. Actively participate in lab management activities


  • Knowledge of protein purification techniques.

  • Experience in protein process development.

  • Knowledge of analytical tools for analysis of proteins.

  • Experience with DOE (design of experiments), six sigma, and lean manufacturing a plus.

  • Knowledge of GMPs.

  • Good interpersonal skills, good verbal and written communication skills. Able to work in cold environment.

Education and/or experience

Bachelor or Master Degree in a scientific discipline with at least 2+ year s relevant experience.

Physical Demands

  • Must be able to push/pull 50 lbs. and lift/carry up to 25 lbs.
  • In general, the position requires a combination of sedentary work and walking around observing conditions in the facility.

Working Environment

  • Must be able to work in controlled environments requiring special gowning. Will be required to follow gowning requirements and wear protective clothing over the head, face, hands, feet and body.
  • No make-up, jewelry, contact lenses, nail polish or artificial fingernails may be worn in the manufacturing environment.
  • Will work in a cold, wet environment.
  • Must be able to work multiple shifts, including weekends.
  • May be required to work in a confined area.
  • Some Clean Room and cool/hot storage conditions.

Notice to Employment / Recruitment Agents:

Employment / Recruitment agents may only submit candidates for vacancies only if they have written authorization to do so from Shire, a wholly-owned subsidiary of Takeda s Talent Acquisition department. Any agency candidate submission may only be submitted to positions opened to the agency through the specific Agency Portal. Shire, a wholly-owned subsidiary of Takeda will only pay a fee for candidates submitted or presented where there is a fully executed contract in place between the Employment / Recruitment agents and Shire, a wholly-owned subsidiary of Takeda and only if the candidate is submitted via the Agency Portal. Candidates submitted or presented by Employment / Recruitment Agents without a fully executed contract or submitted through this site shall not be deemed to form part of any Engagement for which the Agency may claim remuneration.

Equal Employment Opportunity

Shire, a wholly-owned subsidiary of Takeda, is an Equal Opportunity Employer committed to a diverse workforce. Shire, a wholly-owned subsidiary of Takeda, will not discriminate against any worker or job applicant on the basis of race, color, religion, gender, national origin, ancestry, age, sexual orientation, marital or civil partnership status, pregnancy, gender reassignment, non-job related mental or physical disability, genetic information, veteran status, military service, application for military service, or membership in any other category protected under law.

EEO is the Law -

EEO is the Law Supplement -

Pay Transparency Policy -

Reasonable Accommodations

Shire, a wholly-owned subsidiary of Takeda, is committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please call 484-595-8400 and let us know the nature of your request and your contact information.

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  considered, please do so. Applications for all positions are subject to each employer's specific requirements.