Posted to MedZilla on 3/25/2019

Takeda Pharmaceuticals

US-MA, 2019 Summer Internship - Drug Safety Research & Evaluation R0007003-MZ


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Job Description


Intern, Global Drug Safety Research & Evaluation, Takeda (Cambridge, MA)


Optimize in vitro assays for detection of cardiac risk.


Cardiotoxicity is the leading cause of safety-related attrition for new drugs. Join Takeda s Investigative Toxicology team for a semester and help our team develop & validate new tools to predict cardiotoxicity. We are testing the ability of cutting edge technologies (human stem cell derived cardiomyocytes, functional electrophysiological assays, high content analysis, gene expression) to predict a diverse array of cardiotoxicities. The successful applicant will help us build a bridge between our cellular models and clinical and preclinical in vivo studies through analysis of published data on marketed compounds and in-house study reports on Takeda molecules.

Experience Gained

Students will gain real-world experience working as part of a drug discovery team. Laboratory work will include the development of in vitro assays using stem cell derived cardiomyocytes. Instruction and mentorship will be provided by cardiovascular toxicology scientists.

Experience Wanted

Education: The incoming intern will have completed their at least their sophomore year of college (biology / biochem / biomedical sciences/engineering preferred).

Relevant experience: Experience with laboratory methods required (mammalian cell culture) and data analysis (preferably MATLAB, R or Python) sought.


Boston, MA

Worker Type


Worker Sub-Type

Paid Intern (Fixed Term) (Trainee)

Time Type

Full time

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