US-MA, 2019 Summer Internship - Drug Safety Research & Evaluation R0007003-MZ
Intern, Global Drug Safety Research & Evaluation, Takeda (Cambridge, MA)
Optimize in vitro assays for detection of cardiac risk.
Cardiotoxicity is the leading cause of safety-related attrition for new drugs. Join Takeda s Investigative Toxicology team for a semester and help our team develop & validate new tools to predict cardiotoxicity. We are testing the ability of cutting edge technologies (human stem cell derived cardiomyocytes, functional electrophysiological assays, high content analysis, gene expression) to predict a diverse array of cardiotoxicities. The successful applicant will help us build a bridge between our cellular models and clinical and preclinical in vivo studies through analysis of published data on marketed compounds and in-house study reports on Takeda molecules.
Students will gain real-world experience working as part of a drug discovery team. Laboratory work will include the development of in vitro assays using stem cell derived cardiomyocytes. Instruction and mentorship will be provided by cardiovascular toxicology scientists.
Education: The incoming intern will have completed their at least their sophomore year of college (biology / biochem / biomedical sciences/engineering preferred).
Relevant experience: Experience with laboratory methods required (mammalian cell culture) and data analysis (preferably MATLAB, R or Python) sought.
Paid Intern (Fixed Term) (Trainee)
Please visit our website at takedajobs.com