Posted to MedZilla on 7/19/2018


Takeda Pharmaceuticals

US-MA, Scientist, Process Chemistry R0002654-MZ


 
 

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Job Description

Are you looking for a patient-focused company that will inspire you and support your career? If so, be empowered to take charge of your future at Takeda. Join us as a Scientist/Research Investigator, Process Chemistry in our Cambridge office.

Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. As a Scientist/Research Investigator working on the Process Chemistry team, you will be empowered to push the boundaries of synthetic chemistry and innovate in drug development, and a typical day will include:

  • Designing and obtaining laboratory proof of concept for new, concise synthetic routes to challenging drug substance targets
  • Developing safe, efficient and robust chemical processes for drug substance manufacture
  • Partnering with our Pharmaceutical Sciences colleagues and our external supply chain to bring new experimental medicines to the clinic
  • Working in a highly collaborative and empowering environment on stimulating scientific and technical problems

POSITION OBJECTIVES:

  • Provides theoretical/conceptual input to the design, development and execution of research assignments for a specific project or projects within the functional area.
  • Independently plans and executes most unit operation characterization and optimization experiments within expertise and develops an awareness of unit operations in other areas.
  • Responsible for significant or sole technical leadership within project or complex study.
  • Prepares technology transfer documentation and regulatory documents or coordinates with team members to ensure execution.
  • Represents line functions on GCT teams as appropriate/necessary.
  • Proactively identifies process or study issues/challenges and proposes potential resolutions.

POSITION ACCOUNTABILITIES:

  • Understands project timelines and deliverables and plans/coordinates project work accordingly with departmental, functional and external stakeholders
  • Provides technical leadership to project teams within area of expertise and commits resources to execute specific project tasks.
  • Contributes significantly and independently to project work which may include multiple projects within functional area.
  • Reviews, interprets and communicates data cross-functionally within CMC and/or project teams.
  • Plans and implements resolutions to technical problems/issues
  • Represents functional area on GCT project teams by communicating activities from designated functional area to project team
  • Supports local and global initiatives which may include leading initiatives or work streams
  • Serves as a technical resource for junior staff and leverages expertise in laboratory technology as a functional resource/trainer.
  • Independently designs and executes experiments, and reports results
  • Assists with development of project strategy and communicates complex data/decisions within department and cross functionally as necessary
  • Builds and maintains relationships with key vendors and assists with technical aspects of vendor negotiations
  • Proactively analyses manufacturing issues and coordinates potential resolution with the CMC team.
  • Responsible for integrating scientific/technical efforts around cross-functional issues

EDUCATION, EXPERIENCE, BEHAVIOURAL COMPETENCIES AND SKILLS:

Education Required to be Considered at the Scientist Level:

  • Bachelors degree in chemistry or related pharmaceutical science and 8+ years relevant industry experience
  • Masters degree in chemistry or related pharmaceutical science; 6+ years relevant industry experience
  • PhD in chemistry or related pharmaceutical science; 0-2+ years relevant industry experience

Education and Experience Required to be Considered at the Research Investigator Level:

  • Bachelors degree in chemistry or related pharmaceutical science; 5+ years relevant industry experience
  • Masters degree in chemistry or related pharmaceutical science; 2-3+ years relevant industry experience
  • Previous experience working in lab setting

Knowledge and Skills:

  • In depth knowledge of modern synthetic organic chemistry.
  • Advanced proficiency in route scouting, reaction optimization, synthetic methodology development, and/or elucidation of mechanism.
  • Proficiency with analytical tools (e.g. HPLC, GC, NMR, UV, IR, MS, etc.)
  • Proficiency with utilizing typical literature searching techniques to solve organic chemistry problems
  • Analytical and Problem-Solving Skills - Able to troubleshoot critical issues or problems, and determine causes and possible solutions
  • Teamwork -- Ability to work well in highly cross functional team environment and across global line functions.
  • Communication Skills -Able to expresses one s self clearly and concisely within team; documents issues and/or concerns concisely with colleagues; adjusts communication style as appropriate for the audience; timely and effectively communicates issues to supervisor; technical writing skills to support authorship of internal technical documents
  • Organization Exercises good time management and prioritization skills and can successfully manage multiple tasks simultaneously
  • Knowledge Sharing - Ability to capture organizational knowledge; improve solutions, processes, and deliverables through use of information; improve information capital by contributing experience, theories, deliverables, and models for others to use
  • Resource Management -Ability to manage one s time within individual, departmental, and corporate goals and timelines; management of internal and external resources (vendors)
  • External Involvement Demonstrated involvement in professional community evidenced by presentation of scientific posters or lectures at professional conferences or events
  • Technical - Subject matter expertise and knowledge of applicable lab equipment and operations

TRAVEL REQUIREMENTS:

  • May require approximately 5-10% travel.

WHAT TAKEDA CAN OFFER YOU:

  • 401(k) with company match and Annual Retirement Contribution Plan
  • Tuition reimbursement
  • Company match of charitable contributions
  • Health & Wellness programs including onsite flu shots and health screenings
  • Generous time off for vacation and the option to purchase additional vacation days
  • Community Outreach Programs

Empowering Our People to Shine

Learn more at takedajobs.com.

No Phone Calls or Recruiters Please.

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