Posted to MedZilla on 12/18/2018

Takeda Pharmaceuticals

US-MA, Senior Scientist DMPK R0000664-MZ


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Job Description

Are you looking for a patient-focused company that will inspire you and support your career? If so, be empowered to take charge of your future at Takeda. Join us as a Senior Scientist in our Cambridge office.

Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. As a Senior Scientistworking on the DMPK team, you will be empowered to sit on multifunctional project teams to provide DMPK support and design DMPK studies, and a typical day will include:


We are seeking a highly motivated and well accomplished scientist in pharmacokinetics to join the Drug Metabolism and Pharmacokinetics (DMPK) Department of Takeda Pharmaceuticals in Cambridge, MA. This scientist will sit on multi-functional project teams to provide DMPK support to the discovery and development of biologics programs with focuses on immune-oncology therapeutics and target-delivery platforms. The support includes engaging with colleagues across Immunology/Oncology R&D to ensure rapid and thorough translation from pre-clinical studies to clinical studies, and supplying dose predictions of efficacy and safety in patients. Experience in immuno-oncology and biotherapeutics is desirable. Some experience and expertise in modeling such as PK/PD and PBPK is desirable plus.


  • Represent DMPK in discovery and development biologics project teams. Initiate and engage in multifunctional collaborations to facilitate the advancement of drug candidates and build thorough knowledge of biologics properties
  • Be responsible for the design and interpretation of DMPK studies necessary for the selection of clinical candidates
  • Play a visible role in global DMPK to share learning and enhance consistency in best practices across sites and disease areas about targeted therapeutics/biologics discovery and development
  • Keep up to date with emerging literature and science in the biologics development in oncology


  • Ph.D. degree in Pharmacokinetics, Pharmaceutical Sciences, Immunology, Pharmacology, or related discipline;
  • 5+ year industrial experience with demonstrated impact on biologics and/or ADC drug discovery and/or development.
  • Thorough understanding of the basic principles of pharmacokinetics of biologics and/or ADC Prior project leadership experience in antibody drug development preferred
  • Track record of scientific accomplishment as evidenced by quality and quantity of publications and/or inventions
  • Excellent written and oral communication skills to effectively communicate complex research findings and recommendations, and seek to excel in a multi-disciplinary team environment.
  • Ability for critical thinking and strong analytical skills to evaluate complex information for the identification of key scientific findings related to projects.
  • Ability to prioritize and manage multiple projects and activities while meeting tight deadlines
  • Maintains excellent working relationships with colleagues and collaborators


  • 401(k) with company match and Annual Retirement Contribution Plan
  • Tuition reimbursement
  • Company match of charitable contributions
  • Health & Wellness programs including onsite flu shots and health screenings
  • Generous time off for vacation and the option to purchase additional vacation days
  • Community Outreach Programs

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Cambridge, MA

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Full time

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